UCSF GI DIVISION FACULTY

Marion Peters, M.D.

Professor of Medicine
Chief of Hepatology Research
UCSF

Email:

marion.peters@ucsf.edu

Active Projects:

Translational:
  1. Host-viral interactions in Hepatitis C and Hepatitis B infection. These projects evaluate clinical outcomes and the role of inflammatory cytokines and their receptors using DNA polymorphism analysis and mRNA gene profiling. We will assess the effect of the host response in induction of disease and response to therapy including the effect of alcohol and HIV co-infection
Clinical:
  1. : Clinical studies in the role of alcohol in Hepatitis C infection
  2. Co-infection of HIV patients with Hepatitis B and C
  3. the role of liver disease in HIV infection
These studies evaluate outcome and response to therapy.

Techniques in Use:

  1. Laboratory studies: molecular techniques including DNA preparation; analysis of gene expression at the protein and mRNA level; cell culture techniques of human mononuclear cells including cell isolation, cytokine and immune functional analyses; cellular immunology techniques.
  2. Clinical studies: Design of clinical studies, data /statistical analyses and manuscript preparation.

Recent Publications:

Peters MG, Andersen J, Lynch P, et al, for the ACTG Protocol A5127 Team. Randomized controlled study of tenofovir and adefovir in chronic Hepatitis B virus and HIV coinfection. Hepatology 2006;44:1110-6.

Koziel M and Peters P. Viral Hepatitis in HIV Infection. New Eng J Med, 2007: 356; 1445-1454.