UCSF GI DIVISION FACULTY

Nathan M. Bass, M.D., Ph.D.,

Professor of Medicine
Medical Director, Liver Transplantation, UCSF
University of California, San Francisco

Address:

Box 0538
University of California
San Francico, CA 94143

Email:

nathan.bass@ucsf.edu

Active Projects:

Clinical and translational studies on the pathophysiology of portal hypertension, fatty liver diseases, cholestatic and drug-induced liver diseases, including:
1. Studies of the pathophysiological/genomic basis of nonalcoholic fatty liver disease through the National (NIH) Clinical Research Network for the Study of NASH
2. Therapeutic trials of pharmacological agents and blood products in hepatic encephalopathy, ascites, hyponatremia, coagulopathy and primary biliary cirrhosis
3. Long-term outcomes following liver transplantation through local and National (NIH) Liver Transplant Databases
4. Studies of outcomes and therapeutic intervention trials (NAC and hypothermia) in acute liver failure through the National (NIH) Acute Liver Failure Study Group
5. Therapeutic trials of intravenous albumin and terlipressin in the management of refractory ascites and hepatorenal syndrome

Techniques:

1. Patient-based physiological and hemodynamic studies; prospective, randomized controlled studies; prospective cohort studies; case control studies
2. Application of laboratory molecular technology to defining the pathophysiology of liver disease.

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Recent Publications:

Merriman RB, Aouizerat BE, Bass NM. Genetic Influences in Nonalcoholic Fatty Liver Disease. J Clin Gastroenterol 2006;40:S30-S33.

Merriman RB, Ferrell LD, Patti MG, Weston SR, Pabst MS, Aouizerat BE, Bass NM. Correlation of paired liver biopsies in morbidly obese patients with suspected nonalcoholic fatty liver disease. Hepatology. 2006 Oct;44(4):874-80.