The Lynch Lab advances the understanding of chronic inflammatory diseases and disorders by examining relationships between complex microbial community composition, bacterial behavior and host immune response. The multidisciplinary group includes microbial ecologists, bacterial physiologists and physician scientists, dedicated to applying recently developed culture-independent tools to examine the role of the human microbiome in defining states of health and disease.
Our team is primarily interested in understanding microbial-host interactions in pulmonary and gastrointestinal tracts of patients with chronic inflammatory diseases. We primarily focus our efforts on the following areas of research:
- Structural and functional analyses of the gastrointestinal microbiome in chronic GI inflammatory diseases with a particular focus on ulcerative colitis and Crohn'€™s disease.
- Examination of the impact of early microbial exposure events (including gastrointestinal microbiome manipulation with probiotic species) that shape the developing neonatal immune system and impact subsequent allergic disease development.
- Microbiome abnormalities in inflammatory airway diseases
- Development of culture-independent tools for rapid detection and phenotyping of nosocomial pathogens
For more information on our work read the overview of the Research Group.
For more information about members of the group please visit the Research Group Members page.
The Lynch Lab is located on the UCSF Parnassus Campus. To contact us email:
Susan Lynch <susan.lynch@ucsf.edu>