UCSF GI DIVISION FACULTY

Jacquelyn J. Maher, M.D.

Professor of Medicine
San Francisco General Hospital

Address:

Bldg. 40, Room 4102
San Francisco General Hospital
San Francisco, CA 94110

Email:

jmaher@medsfgh.ucsf.edu

Active Projects:

1. Identifying and testing hepatoprotective agents that prevent acute liver injury or early graft failure in the liver transplant setting.
2. Clarifying the pathogenesis of non-alcoholic steatohepatitis, with particular attention to the role of dietary nutrients.

Techniques in Use:

1. Animal models of acute and chronic liver disease.
2. Primary liver cell culture.
3. Analysis of cell death pathways and inflammatory pathways in liver.
4. Histology, immunohistochemistry, lipid biochemistry.

Recent Publications:

Hanson JC, Bostick MK, Campe CB, Kodali P, Lee G, Yan J, Maher JJ. Transgenic overexpression of interleukin-8 in mouse liver protects against galactosamine/endotoxin toxicity. J Hepatol. 2006 Feb;44:359-67.

Lee GS, Yan JS, Ng RK, Kakar S, Maher JJ. Polyunsaturated fat in the methionine-choline-deficient diet influences hepatic inflammation but not hepatocellular injury. J Lipid Res 2007, epub May 27

Dr. Maher's Biosketch